PRISM Lab
Research
Biomaterials for Advanced Drug Delivery
Research focus: The figure presents a biomaterials-based strategy for advanced drug delivery in which an upconverting nanoparticle is shown converting near-infrared (NIR) excitation into UV/visible emission. The emitted light is used to activate protoporphyrin IX (PPIX), leading to reactive oxygen species (ROS) generation. The accompanying absorbance/emission plots and nanoparticle image visually support the optical and materials characterization of this platform.
Tissue Engineering for In Vitro Tumor Models
Research focus: The visuals show the development of three-dimensional breast tumor models using tumor spheroids, collagen-based environments, and microfluidic devices. These engineered systems provide progressively more structured settings for studying tumor behavior in vitro, while the fluorescent microscopy image illustrates the cellular organization within a 3D tumor model.
Protein Engineering for Cancer Therapeutics
Research focus: The figure contrasts passive and targeted delivery to highlight the goal of directing therapeutic molecules toward tumor tissue while limiting nonspecific accumulation in healthy tissue. The lower molecular and fluorescence images complement this concept by showing protein-level visualization and biological localization relevant to cancer therapeutics.
Molecular Docking and Protein Simulations
Research focus: The video illustrates computational analysis of protein structure and molecular behavior, with views of a 3D protein model, predicted confidence across positions, molecular visualization, and secondary-structure annotations. Together, these views demonstrate how molecular docking and protein simulations can be used to investigate protein structure, interactions, and stability relevant to therapeutic design.